|
|
|
|
Acquired neuromytonia is characterized by hyperexcitability of motor nerves leading to muscle twitching,cramps,and weakness.The symptoms may improve following plasma exchange,and injection of immunoglobulin G(IgG) from 1 neuromyotonia patient into mice increased the resistance og neuromuscular transmission of d-tubocurarine.We conclude that at lease some patients with acquired neuromyotonia have antibodies directed against aminopyridine-or alpha-dendrotoxin-sensitive K+channels in motor and sensory neurons,and they are likely to be implicated in the disease process. |
|